The Stanos metallogenic area, Chalkidiki, North Greece, includes the Paliomylos and Chalkoma Cu-Au ore bodies. The host rocks to the mineralization are quartz-dominated mylonitic zones within the mica-gneisses of the Paleozoic Servomacedonian Massif. Chalcopyrite, pyrrhotite, arsenopyrite, pyrite, magnetite and galena dominate the mineralogy in the ore bodies whereas the identified Bi-Au-Ag-Te mineral associations include electrum, native Bi, joseite, and lillianite homologues. Au-sulfide mineralization is zoned and strongly related to potassic-calcic (biotite-chlorite-sericite-carbonate) alteration. Textural features (i.e. dynamic recrystallization of quartz, sigmoidal quartz boudins, sulphide porphyroblasts along S-C foliation planes, etc) indicate that hydrothermal mineralization occurred during regional northeast-vergent ductile shearing, at upper greenschist-lower amphibolite facies metamorphism.