Calibrations which form the basis for the garnet-biotite geothermometer and account for the effect of nonideality of coexisting garnet and biotite on the distribution coefficient were considered. It is demonstrated that the maximum accuracy of the temperature determination is achieved when using the calibrations founded on the asymmetric subregular garnet solution model with interaction parameters derived by (Ganguly et.al., 1996; Holdaway, 2000), and constructed in terms of experimental data (Perchuk, Lavrent’eva, 1983) as well as the calibrations incorporated additional symmetric regular Phl-biotite solution model with interaction parameters given by (Holdaway et al., 1997; Kaneko, Miyano, 2004; this work), and set in terms of data (Ferry, Spear, 1978; Perchuk, Lavrent’eva, 1983). These calibrations approximate closely the temperature that the equilibrium Grt-Bt reached during experiments, and are least sensitive to variations of Ca and Mn contents in garnet, AlVI č Ti contents in biotite.