|Human calcifications: biotropism, ontogeny and morphostructure|
|RMS-DPI code: ||
|Scientific session: ||
7. Mineralogy in study and conservation of biosphere.|
|Author listing: ||
Evdokimov F.À., Yakushina O.A., Bystrov I.G., Iospa A.V., Gamataev I.I.|
|Principal author: ||
Yakushina Olga Aleksandrovna|
|Abstract - Summary |
|Biogeneous mineral concrements of various localization as stones in human body are alien pathogenic formations that cause a set of dangerous diseases. Among these biogeneous formations are calcifications, bilious and salivary stones. Still there is no consensus on the issue of their origin, but many medical workers connect them with an infectious etiology.
Biogeneous mineral concrements of origin have been for their composition, structure and morphology. Among them are calcifications, other mineral formations. We believe mineralogical base of crystal growth theory as biogeneous stones arise and grow in human body.
We studied on mineralogical approach different calcifications, bilious and salivary stones by optical microscopy, X-ray Computed microTomography X-ray powder diffraction, XPD. X-ray CT benefit is obvious, the method is non-destructive and visualize internal of any object.
Actually mineral concrements display heterogeneous phase composition and morphology, irregular forms twisting edges, and usually have organic tissues in central part. Calcifications consist of 5-6 phases, two belong to an organic fabric (possibly proteins and lipids), other 3-4 mineral phases are wivewnit, hydroxlapatite, hydroxlcarbonateapatite and calcite of different density. The formed and young arising calcifications 30 microns size have been compared. Both organogeneous calcifications have considerable similarity of phase composition, but the young one also contained less than 0,15 wt.% slightly crystallized hydroxlapatite. Thus the young calcification has already initiated the development of atherosclerotic process. XCT tomograms of the salivary stone display morphology similarity to the one of mineral substance, for example ferromanganese nodules or pearls, but differ in phase composition. XPD of various salivary stones detected composition similar to calcifications, but gallastones were of different phase composition.
Biogeneous concrements calcifications, salivary stones and gallstones differ in phase composition and morphology, mechanisms of their nucleation and grows. The used mineralogical approach is alike histology in medical and biological studies, but may better promote disease courses explanation, revealing mechanisms of the calcification process development, being aimed at the human health protection.
biolithos, calcifications, gallstones, salivary stones, testing methods, Õ-ray ÑÒ, morphostructure, composition, morphology
|RMS-DPI code: ||
|File of proceedings |
|Published on-line: ||
|Permanent address of publication: ||
|Contact author(s): ||
Yakushina, Olga Aleksandrovna|